Name | Thiophene-2-thiol |
Synonyms | Thiophenethiol Thiophene-2-thiol 2-Mercaptothiophene 2-Thienyl mercaptan 2-Mercaptothi ophene 2-Mercapto thiophene |
CAS | 7774-74-5 |
EINECS | 231-881-1 |
InChI | InChI=1/C4H4S2/c5-4-2-1-3-6-4/h1-3,5H |
InChIKey | SWEDAZLCYJDAGW-UHFFFAOYSA-N |
Molecular Formula | C4H4S2 |
Molar Mass | 116.205 |
Density | 1.269g/cm3 |
Boling Point | 166.9°C at 760 mmHg |
Flash Point | 54.7°C |
Vapor Presure | 2.3mmHg at 25°C |
pKa | 6.38±0.43(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.636 |
Physical and Chemical Properties | boiling point 62 ℃ (12 torr) density 1.23 |
Risk Codes | R21/22 - Harmful in contact with skin and if swallowed. R36/38 - Irritating to eyes and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
UN IDs | UN3334 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-13-23 |
HS Code | 29349990 |
Hazard Class | 9 |
Packing Group | III |
Properties:
1. Thiophene-2-thiol is a colorless to pale yellow liquid with a pungent odor.
2. It exhibits strong reducing properties and can be easily oxidized to carbon disulfide.
3. It can turn deeper yellow and is volatile in air.
Uses:
1. Thiophene-2-thiol plays an important role as an organic sulfur compound in organic synthesis, serving as a raw material or intermediate for the synthesis of other organic sulfur compounds.
2. It is commonly used as a catalyst, coordination ligand, or redox reagent.
3. It can be used as an introduction reagent for sulfur-containing ring systems in certain chemical reactions.
Synthesis:
Thiophene-2-thiol is typically prepared by reacting thiophene with sodium sulfide or hydrogen sulfide. The specific synthesis method involves dissolving thiophene in a sodium hydroxide solution, bubbling hydrogen sulfide gas through the reaction mixture, and then isolating and separating the final product through appropriate extraction and purification steps.
Safety:
1. Thiophene-2-thiol has a pungent odor and should be kept away from skin and eyes to avoid contact.
2. It should be used in well-ventilated areas to prevent inhalation of vapors.
3. Avoid contact with oxygen or oxidizing agents during handling and storage to reduce the risk of fire and explosion.
4. Thiophene-2-thiol is toxic, so proper protective measures should be taken during use, such as using protective eyewear and gloves.
FEMA | 3062 | 2-THIENYL MERCAPTAN |
Sensitivity | Air Sensitive |
JECFA Number | 1052 |
BRN | 104650 |
Hazard Note | Irritant |